Institute of Neurological Sciences and Psychiatry Laboratory Facilities and Research Areas:
The Institute of Neurological Sciences and Psychiatry is a distinguished centre of scientific excellence and multidisciplinary approach to project-based research for the understanding and treatment of neurological disorders. The various techniques and research areas in our laboratories play an important role in the development of innovative and effective treatment methods for neurological and psychiatric disorders.
in vivo Laboratory: In the in vivo laboratory of our institute, various neurological and psychiatric diseases such as brain and retinal stroke, migraine aura, brain stimulation with optogenetic method, neuroinflammation, microcirculation, brain tumours, head trauma, epilepsy, sleep disorders, pain models, acute-chronic stress, depression, autism, Parkinson's disease, Alzheimer's disease are successfully modelled. Wild-type and different types of transgenic mice and rats are used in disease models. These animal models form an important basis for understanding the complex mechanisms of diseases and developing effective treatment methods.
in vitro Laboratory: Molecular and histological analysis methods such as Western blotting, PCR, immunohistochemical and immunofluorescent labelling and ELISA are used in our institute.
Cell Culture Laboratory: Experiments are performed with primary and commercial cell lines. Primary cell culture from human brain tumour tissue and 2D and 3D cell culture models created with various cell lines are used. In vitro spinal cord trauma is modelled with organotypic culture.
Imaging Laboratory: State-of-the-art imaging techniques such as confocal microscope, epifluorescence and light microscopes are used in our institute. Thanks to these technological facilities, detailed analyses on the pathophysiology of neurological diseases are performed.
Behaviour Laboratory: In the behavioural laboratory of our institute, various behavioural tests are applied to understand the behavioural reflections of neurological and psychiatric diseases. These tests mediate the evaluation of the effects of diseases on cognitive, affective and motor functions and the effectiveness of therapeutic interventions.
Laboratory Safety Manual: